Irasto Treatment Guidance

Total Knee Replacement

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Introduction to Total Knee Replacement

Total Knee Replacement (TKR), also known as Knee Arthroplasty, is a surgical procedure that is performed to replace the worn-out or damaged surfaces of the knee joint. This surgery is typically recommended for patients suffering from severe arthritis or a serious knee injury. Over the years, TKR has evolved with advancements in surgical techniques and prosthetic design, significantly improving the outcomes for patients.


The goal of a Total Knee Replacement is to relieve pain, restore alignment and function, and return patients to their normal activities with improved quality of life. During the procedure, the orthopedic surgeon removes the damaged cartilage and bone from the surface of your knee joint and replaces them with an artificial joint made from metal and plastic composites. This artificial joint is designed to replicate the knee’s natural movement.

Knee replacement is one of the most successful procedures in all of medicine, with hundreds of thousands of surgeries performed each year globally. It is a safe and effective procedure that can relieve pain, correct leg deformity, and help patients resume normal activities.

The decision to proceed with knee replacement surgery is a cooperative one between you, your family, your primary care doctor, and your orthopedic surgeon. The process leading to surgery is multifaceted, involving a comprehensive evaluation, a detailed explanation of the procedure, understanding the recovery process, and considering the overall impact on the patient’s life.

The journey to a new knee begins with understanding your condition and the treatment options available. With successful surgery and rehabilitation, Total Knee Replacement can be a life-transforming procedure, allowing individuals to regain lost mobility and enjoy a pain-free life.

Understanding Knee Joint Degeneration

Knee joint degeneration is the progressive loss of the smooth cartilage that covers the ends of the bones in the knee joint. This cartilage serves as a cushion and enables frictionless movement of the joint. When it wears down, bones may rub against each other, causing pain, stiffness, and decreased mobility — a condition often referred to as osteoarthritis. 

The degeneration can be due to a variety of factors, including

  • Age

    The natural aging process can lead to wear and tear of the knee joint over time.

  • Weight

    Being overweight or obese puts extra pressure on knee joints, especially during movement.

  • Gender

    Women over the age of 55 are more prone to developing osteoarthritis.

  • Injuries

    Previous injuries such as fractures, ligament damage, or meniscus tears can lead to joint degeneration.

  • Repetitive Stress

    Jobs or sports that put repetitive stress on the knee joint can contribute to cartilage breakdown.

  • Genetics

    A family history of osteoarthritis or congenital bone deformities can predispose individuals to knee degeneration.

  • Bone Misalignments

    Misaligned bones can cause uneven stress and wear on the knee.

  • Rheumatoid Arthritis

    An autoimmune condition that can cause inflammation and degeneration of the cartilage.

  • Metabolic Diseases

    Conditions like gout and pseudogout can lead to crystalline deposits in the knee joint, leading to degeneration.

As the cartilage deteriorates, the synovial fluid that lubricates the joint becomes less effective, and the space between the bones may narrow. This can result in bone spurs (osteophytes) and can contribute to the pain and loss of function.

Patients with knee joint degeneration may experience symptoms like aching pain, stiffness after periods of inactivity or rest, swelling and warmth in the joint, decreased mobility, and a crunching or grinding sound during movement.

Understanding knee joint degeneration is pivotal for early intervention and to prevent further damage. Treatment options can vary from conservative methods like weight management and physiotherapy to medical interventions including corticosteroid injections and ultimately, surgical options such as Total Knee Replacement when the joint’s condition severely impacts the patient’s quality of life.

Indications for Total Knee Replacement

Total Knee Replacement (TKR), also known as knee arthroplasty, is considered when less invasive treatments have failed to provide relief from chronic knee pain and impaired function. It is a surgical procedure that involves replacing the damaged or diseased parts of the knee joint with artificial components. The typical indications for a TKR include:
  • Severe Knee Pain

    Pain that limits or completely prevents everyday activities, including walking, climbing stairs, and even resting or sleeping.

  • Moderate to Severe Pain While Resting

    This level of pain is present even during rest and at night, often indicating more advanced joint degeneration.

  • Chronic Inflammation and Swelling

    Persistent inflammation that does not improve significantly with medication or rest.

  • Knee Deformity

    A bowing in or out of the knee that signifies advanced joint disease or deterioration.

  • Degenerative Joint Disease

    Severe osteoarthritis is a prime reason for TKR, especially when it leads to joint space narrowing and bone damage.

  • Rheumatoid Arthritis

    When the immune system attacks the lining of the joint, causing pain and stiffness.

  • Post-traumatic Arthritis

    Arthritis that develops after an injury to the knee, such as a fracture or ligament damage, which has altered the joint structure.

  • Failed Previous Knee Surgery

    When less invasive surgeries like arthroscopy or partial knee replacements have not been successful.

  • Ineffective Non-Surgical Treatments

    When medications, physical therapy, knee injections, and the use of walking supports no longer effectively manage knee symptoms.

  • Reduced Quality of Life

    When the knee pain and dysfunction significantly impair one’s ability to perform routine activities and affect their quality of life.

It is crucial to note that the decision for TKR is made after a comprehensive assessment by an orthopedic surgeon who will evaluate the extent of knee damage, the patient’s overall health, age, activity level, and the potential risks and benefits of the surgery. The main goal of TKR is to relieve pain, improve knee function, and enhance the quality of life.

Types of Knee Replacement Surgeries

Knee replacement surgeries are designed to alleviate pain caused by joint degeneration, primarily due to arthritis or trauma. The type of surgery performed depends on the extent of the knee joint damage. Here are the common types of knee replacement surgeries:
  • Total Knee Replacement (TKR):

    This is the most common type of surgery, where all the weight-bearing surfaces of the knee joint are replaced with an artificial implant. It’s suitable for patients with severe arthritis affecting multiple compartments of the knee.

  • Partial Knee Replacement (PKR):

    Also known as unicompartmental knee replacement, this procedure involves replacing only one part of the knee joint (either the medial, lateral, or patellofemoral compartment). It’s best for patients whose damage is limited to a specific area of the knee.

  • Revision Knee Replacement:

    This surgery is done to replace an old knee prosthesis that has become loose, infected, or worn out.

  • Kneecap Replacement (Patellofemoral Arthroplasty):

    This is the replacement of just the underside of the kneecap and the groove it sits in when it’s the only area affected by arthritis.

  • Complex or Revision Knee Replacement:

    This is required for patients with severe bone loss or deformity, often due to previous surgeries, severe arthritis, or fractures. It involves more extensive reconstruction.

  • Computer-Assisted Surgery (CAS):

    Technological advancements have led to the development of CAS, which provides the surgeon with real-time 3D images of the knee joint during surgery for more precise implant placement.

  • Robot-assisted Knee Replacement:

    In this type, a robotic arm is used to assist the surgeon in the removal and replacement of joint components, enhancing precision and potentially improving outcomes.

  • The type of knee replacement surgery is chosen after thorough diagnostic imaging, consideration of the patient's lifestyle, and personal goals post-surgery.

    The objective is always to restore function, reduce pain, and improve the quality of life for the patient.

Preparing for Your Knee Replacement

The journey to a successful knee replacement begins well before the surgery day. Adequate preparation can ensure a smoother operation and recovery. The following are steps to prepare for your knee replacement:

  • 1. Preoperative Medical Evaluation

    A comprehensive health check, including blood tests, cardiac workup, and a review of medications, will be conducted to optimize your health status for surgery.

  • 2. Physical Preparation

    Strengthening exercises may be prescribed to improve surgical outcomes. Building upper body strength can also be beneficial for mobility during recovery.

  • 3. Home Arrangements

    Make sure your home is ready for your post-surgery needs. This may include installing safety bars in the shower, securing rugs to prevent slips, and creating a living space on ground level to avoid stairs.

  • 4. Nutritional Planning

    A well-balanced diet can aid in healing. Pre-planning meals for post-surgery, possibly with the help of a nutritionist, can ensure you get the necessary nutrients without the stress of meal preparation.

  • 5. Equipment

    Obtain any equipment you'll need post-surgery such as a walker, cane, or raised toilet seat. Learning how to use these aids in advance can be helpful.

  • 6. Support System

    Arrange for help around the house for a few weeks post-surgery. This includes assistance with cooking, cleaning, and transportation.

  • 7. Anesthesia Discussion

    You will meet with the anesthesiologist to discuss the types of anesthesia available and determine the best option for your situation.

  • 8. Medication Review

    Some medications may need to be paused or adjusted before the surgery. Discuss all your medications with your doctor, including over-the-counter drugs and supplements.

  • 9. Quitting Smoking

    Smoking can delay wound healing and recovery. If you smoke, it's advisable to quit several weeks before the surgery.

  • 10. Mental Preparation

    Mental resilience can significantly impact your recovery. Engaging in stress-reducing activities such as meditation or counseling can be beneficial.

  • Preparing for knee replacement is not solely about the surgical procedure; it's also about setting up a conducive environment for recovery and ensuring that you, as the patient, are mentally and physically ready for the journey ahead.

The Knee Replacement Procedure

Total knee replacement, also known as knee arthroplasty, is a surgical procedure where the damaged knee joint is replaced with artificial components. 

A step-by-step breakdown of the procedure is as follow,

  • Anesthesia

    The procedure usually requires general anesthesia, so you will be asleep and feel no pain. In some cases, spinal or epidural anesthesia may be used to numb the lower body.

  • Incision

    The surgeon makes an incision in the knee area to access the joint.

  • Removal of Damaged Joint Surfaces

    The damaged cartilage surfaces at the ends of the femur and tibia are removed along with a small portion of the underlying bone.

  • Preparation of Joint Surface

    The newly exposed surfaces of the femur and tibia are then prepared to fit the specifically designed metal or ceramic components that will mimic the function of the knee.

  • Implanting the Prosthesis

    The metal implants are either cemented or "press-fit" into the bone. The surgeon will choose the method that's best for your situation.

  • Resurfacing the Patella

    Depending on the case, the underside of the patella (kneecap) may be cut and resurfaced with a plastic button.

  • Inserting a Spacer

    A medical-grade plastic spacer is inserted between the metal components to create a smooth gliding surface.

  • Closing the Incision

    Once the components are fixed in place, the incision is closed with sutures or staples.

  • Postoperative Care:

    You’ll be moved to a recovery area where you’ll be closely monitored as you recover from anesthesia.

The procedure typically takes a couple of hours. After surgery, you will be encouraged to move your new joint almost immediately. Physical therapy starts within the first day post-op, which is crucial for recovery and to quickly regain knee function.

Benefits of Knee Replacement

Knee replacement surgery, or knee arthroplasty, offers a significant improvement in quality of life for patients suffering from degenerative knee diseases. Here’s an overview of the benefits:
  • Pain Relief

    The most immediate and impactful benefit for patients is the substantial reduction or complete elimination of knee pain.

  • Improved Mobility

    Patients often experience a significant improvement in mobility, allowing them to participate in daily activities with greater ease and comfort.

  • Correction of Deformity

    Knee replacement can correct leg deformity by realigning the legs to their natural position.

  • Enhanced Quality of Life

    With pain relief and improved mobility, patients generally find a marked improvement in their overall quality of life.

  • Increased Activity Level

    Many patients are able to return to activities such as walking, swimming, biking, and other low-impact sports they previously found difficult or impossible.

  • Long-term Solution

    Knee replacements can last for many years, with modern prostheses often lasting 15-20 years or more, making it a long-term solution to knee problems.

  • Improved Mental Health

    Chronic pain is often associated with depression and anxiety; relief from pain can lead to significant improvements in mental health.

It’s important to note that while knee replacement can provide significant benefits, it is typically recommended after other treatments have failed to provide relief, as it is a major surgery and comes with the risks associated with surgical procedures.

Potential Risks and Complications of Knee Replacement

While knee replacement surgery is generally safe and effective, like any major surgical procedure, it carries potential risks and complications. Patients should be aware of these possibilities:
  • Infection

    Although rare, there is a risk of infection at the site of the incision or within the joint space.

  • Blood Clots

    The formation of blood clots in the veins of the leg (deep vein thrombosis) can be a serious complication, with the potential for clots to travel to the lungs (pulmonary embolism).

  • Implant Problems

    While modern implants are durable, they can wear down or loosen over time, potentially requiring a revision surgery.

  • Nerve Damage

    During surgery, nerves around the knee may be damaged, potentially leading to numbness or changes in sensation.

  • Blood Vessel Injury

    Blood vessels near the surgical site can be injured, leading to bleeding and vascular complications.

  • Anesthesia Risks

    Reactions to anesthesia or problems from medications used during surgery can occur.

  • Stiffness

    Some patients may experience stiffness in the knee, which might require additional therapy or interventions.

  • Pain

    Not all patients achieve complete relief from pain after surgery, and some may continue to experience some level of discomfort.

  • Allergic Reactions

    On rare occasions, patients might have an allergic reaction to the metal components in the artificial joint.

  • Fracture

    A fracture of the bone around the implant may occur during or after surgery, possibly requiring further surgical intervention.

It’s important for patients to discuss these potential risks and complications with their surgeon to make an informed decision about knee replacement surgery. The surgeon will also take measures to mitigate these risks as much as possible, including preoperative planning, surgical technique, and postoperative care.

Recovery and Rehabilitation After Knee Replacement

Recovery and rehabilitation are critical components following a total knee replacement. Here’s an outline of what patients can expect:
  • 1. Immediate Postoperative Period

    Initially, patients will spend a few hours in the recovery room. As the anesthesia wears off, efforts to control pain and prevent complications, such as blood clots, begin.

  • 2. Hospital Stay

    Most patients stay in the hospital for 1 to 3 days post-surgery. During this time, pain management is a priority, and mobility is encouraged as soon as possible with the help of physical therapists.

  • 3. Physical Therapy

    A physical therapist will guide patients through exercises to strengthen the knee and restore movement. This may start with simple activities like dangling the legs over the side of the bed and progress to standing and walking with assistance.

  • 4. Pain Management

    Patients will receive medications to manage pain. It's crucial to control pain to participate effectively in physical therapy.

  • 5. Home Recovery

    Once home, patients should continue with prescribed exercises, increase their activity level gradually, and monitor the surgical site for signs of infection.

  • 6. Follow-Up Care

    Regular follow-up appointments with the orthopedic surgeon are important to monitor the healing process and the functioning of the knee implant.

  • 7. Ongoing Rehabilitation

    Outpatient physical therapy usually continues for weeks to months, focusing on improving range of motion, strength, and functional mobility.

  • 8. Lifestyle Modifications

    Patients are advised to avoid high-impact activities to prolong the life of the implant but are encouraged to engage in low-impact exercises such as walking, swimming, or cycling.

  • 9. Long-Term Recovery:

    Full recovery and the return to regular, daily activities can take 3 to 6 months, with continual improvement up to a year post-surgery.

  • 10. Support Systems

    Utilizing support from home health services, outpatient therapists, and community resources can be beneficial for a smooth recovery.

  • Each patient’s recovery timeline will vary based on their health, the complexity of the surgery, and their commitment to the rehabilitation process. The ultimate goal of recovery and rehabilitation is to return to a more active and pain-free lifestyle

Cost and Insurance Considerations for Knee Replacement in India

Navigating the financial aspects of a knee replacement is crucial for patients. Here is a detailed overview of what one should know regarding the cost and insurance considerations in India:
  • 1. Procedure Cost Variability

    The cost for total knee replacement surgery in India can vary widely depending on factors like the choice of hospital, city, type of implant, surgeon's fees, and the extent of surgery needed.

  • 2. Hospital Type and Location

    Multi-specialty hospitals in metropolitan cities may charge more than smaller, specialized centers in less urban areas, reflecting differences in infrastructure and the cost of living.

  • 3. Type of Implant

    The choice between a standard implant and a more advanced option can significantly affect the overall cost. Advanced implants, which may offer greater longevity and range of motion, tend to be more expensive.

  • 4. Surgeon's Expertise

    Renowned and highly experienced orthopedic surgeons may charge higher fees, which contribute to the surgery's total cost.

  • 5. Insurance Coverage

    Many health insurance policies in India cover knee replacement surgery. However, it is important to check the specifics of your policy regarding coverage limits, co-pays, and deductibles.

  • 6. Pre- and Postoperative Expenses

    Beyond the surgery itself, patients must consider the cost of preoperative consultations, postoperative rehabilitation, medication, and potential home care services.

  • 7. Cashless Facility

    Some hospitals offer a cashless facility if they have a tie-up with the patient's health insurance company, which can streamline the payment process.

  • 8. Additional Costs

    Miscellaneous costs such as hospital stay, operating room fees, anesthesia, and surgical accessories should also be accounted for.

  • 9. Financial Planning

    It's advisable for patients to speak with hospital billing departments and insurance providers to obtain a detailed understanding of the anticipated costs and coverage.

  • 10. Hidden Costs

    Patients should inquire about potential hidden costs, such as extended hospital stays, unexpected medical complications, and additional post-surgery therapies.

  • 11. Package Deals

    Some hospitals offer comprehensive packages for knee replacement that cover a range of services, which can be more cost-effective than paying for each service individually.

Frequently Asked Questions

Total Knee Replacement (TKR) is a surgical procedure where damaged surfaces of the knee joint are replaced with artificial parts to relieve pain and restore function.
Candidates typically suffer from severe knee pain or stiffness that limits everyday activities, including walking, climbing stairs, and getting in and out of chairs. It is often the result of arthritis or injury.
Most knee replacements are designed to last more than 15 years, though this depends on the patient's activity levels and the implant's wear and tear.
Implants are typically made from metal alloys, ceramic material, and strong plastic parts.
While knee replacement is generally safe, risks include infection, blood clots, implant loosening, and continued pain.
Recovery can vary, but most people can resume normal activities within 6 weeks, with complete recovery taking 3-6 months.
Yes, physical therapy is a crucial part of the recovery process to regain knee strength and motion.
The cost varies but typically ranges from INR 1.5 lakhs to 4 lakhs, depending on the hospital and the type of implant.
Most health insurance plans cover knee replacement surgery, but it is important to check with your provider for specific coverage details.
Some people are able to kneel after recovery, while others find it uncomfortable. Modifications in kneeling positions can be discussed with a therapist.
These questions are intended to provide a comprehensive understanding of Total Knee Replacement, but patients are always encouraged to ask their surgeon any specific questions they have to gain a clear expectation of the procedure, outcomes, and maintenance.